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Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment.
Ng, Chean Hui; Rullah, Kamal; Abas, Faridah; Lam, Kok Wai; Ismail, Intan Safinar; Jamaludin, Fadzureena; Shaari, Khozirah.
Afiliación
  • Ng CH; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia (UPM), Serdang 43400, Selangor, Malaysia. nch_chean@hotmail.com.
  • Rullah K; School of Pharmacy, Management and Science University (MSU), University Drive, Off Persiaran Olahraga, Seksyen 13, Shah Alam 40100, Selangor, Malaysia. nch_chean@hotmail.com.
  • Abas F; Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia. kamalrullah@yahoo.co.id.
  • Lam KW; Nanotechnology and Catalysis Research Centre (NANOCAT), Institute of Postgraduates Studies, University of Malaya (UM), Kuala Lumpur 50603, Malaysia. kamalrullah@yahoo.co.id.
  • Ismail IS; Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia (UPM), Selangor Darul Ehsan, Serdang 43400, Selangor, Malaysia. faridah_abas@upm.edu.my.
  • Jamaludin F; Faculty of Pharmacy, Universiti Kebangsaan Malaysia (UKM), Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia. david_lam@ukm.edu.my.
  • Shaari K; Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia (UPM), Serdang 43400, Selangor, Malaysia. safinar@upm.edu.my.
Molecules ; 23(10)2018 Sep 30.
Article en En | MEDLINE | ID: mdl-30274341
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetofenonas / Glycine max / Inhibidores de la Lipooxigenasa / Lipooxigenasa / Proteínas de Soja Tipo de estudio: Prognostic_studies Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Malasia
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetofenonas / Glycine max / Inhibidores de la Lipooxigenasa / Lipooxigenasa / Proteínas de Soja Tipo de estudio: Prognostic_studies Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Malasia