Antagonism of Transient Receptor Potential Ankyrin Type-1 Channels as a Potential Target for the Treatment of Trigeminal Neuropathic Pain: Study in an Animal Model.

Demartini, Chiara; Greco, Rosaria; Zanaboni, Anna Maria; Francesconi, Oscar; Nativi, Cristina; Tassorelli, Cristina; Deseure, Kristof

Demartini, Chiara; Greco, Rosaria; Zanaboni, Anna Maria; Francesconi, Oscar; Nativi, Cristina; Tassorelli, Cristina; Deseure, Kristof.

Afiliación

Demartini C; Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Center, IRCCS Mondino Foundation, via Mondino 2, 27100 Pavia, Italy. chiara.demartini@mondino.it.
Greco R; Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Center, IRCCS Mondino Foundation, via Mondino 2, 27100 Pavia, Italy. rosaria.greco@mondino.it.
Zanaboni AM; Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Center, IRCCS Mondino Foundation, via Mondino 2, 27100 Pavia, Italy. annamaria.zanaboni@mondino.it.
Francesconi O; Department of Brain and Behavioral Sciences, University of Pavia, via Bassi 21, 27100 Pavia, Italy. annamaria.zanaboni@mondino.it.
Nativi C; Department of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino (FI), Italy. oscar.francesconi@unifi.it.
Tassorelli C; Department of Chemistry 'Ugo Schiff', University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino (FI), Italy. cristina.nativi@unifi.it.
Deseure K; Laboratory of Neurophysiology of Integrative Autonomic Systems, Headache Science Center, IRCCS Mondino Foundation, via Mondino 2, 27100 Pavia, Italy. cristina.nativi@unifi.it.

Int J Mol Sci ; 19(11)2018 Oct 25.

Article en En | MEDLINE | ID: mdl-30366396

Asunto(s)

Dolor/metabolismo; Canal Catiónico TRPA1/metabolismo; Canales Catiónicos TRPV/antagonistas & inhibidores; Canales Catiónicos TRPV/metabolismo; Enfermedades del Nervio Trigémino/metabolismo; Animales; Péptido Relacionado con Gen de Calcitonina/metabolismo; Modelos Animales de Enfermedad; Hiperalgesia/metabolismo; Inmunohistoquímica; Masculino; Ratas; Ratas Sprague-Dawley; Reacción en Cadena en Tiempo Real de la Polimerasa; Sustancia P/metabolismo

Palabras clave

TRPA1; TRPV1; allodynia; neuropathic pain; trigeminal system

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dolor / Enfermedades del Nervio Trigémino / Canales Catiónicos TRPV / Canal Catiónico TRPA1 Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2018 Tipo del documento: Article País de afiliación: Italia

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google