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TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling.
Wolfe, Alan R; Neitz, R Jeffrey; Burlingame, Mark; Suzuki, Brian M; Lim, K C; Scheideler, Mark; Nelson, David L; Benet, Leslie Z; Caffrey, Conor R.
Afiliación
  • Wolfe AR; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 533 Parnassus Ave, San Francisco, CA, 94143, USA; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Neitz RJ; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pharmaceutical Chemistry, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Burlingame M; Department of Pharmaceutical Chemistry, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Suzuki BM; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Lim KC; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Scheideler M; Human First Therapeutics LLC, 9600 Dewitt Drive, Ste 1, Silver Spring, MD, 20910, USA.
  • Nelson DL; Pro-Rectory of Research and Graduate Study, Federal University of the Valleys of Jequitinhonha and Mucuri, 39100-000, Diamantina, MG, Brazil.
  • Benet LZ; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, 533 Parnassus Ave, San Francisco, CA, 94143, USA; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA.
  • Caffrey CR; Center for Discovery and Innovation in Parasitic Diseases, University of California, 1700 4th St, San Francisco, CA, 94158, USA; Department of Pathology, University of California, 1700 4th St, San Francisco, CA, 94158, USA. Electronic address: ccaffrey@ucsd.edu.
Int J Parasitol Drugs Drug Resist ; 8(3): 571-586, 2018 12.
Article en En | MEDLINE | ID: mdl-30503203
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_zoonosis Asunto principal: Schistosoma mansoni / Esquistosomicidas / Profármacos / Arilsulfonatos Límite: Animals Idioma: En Revista: Int J Parasitol Drugs Drug Resist Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_zoonosis Asunto principal: Schistosoma mansoni / Esquistosomicidas / Profármacos / Arilsulfonatos Límite: Animals Idioma: En Revista: Int J Parasitol Drugs Drug Resist Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos