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Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers.
Mori, Daiki; Kashihara, Yushi; Yoshikado, Takashi; Kimura, Miyuki; Hirota, Takeshi; Matsuki, Shunji; Maeda, Kazuya; Irie, Shin; Ieiri, Ichiro; Sugiyama, Yuichi; Kusuhara, Hiroyuki.
Afiliación
  • Mori D; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
  • Kashihara Y; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
  • Yoshikado T; Sugiyama Lab, RIKEN Innovation Center, RIKEN, Yokohama, Japan.
  • Kimura M; Fukuoka Mirai Hospital Clinical Research Center, Fukuoka, 813-0017, Japan.
  • Hirota T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
  • Matsuki S; Fukuoka Mirai Hospital Clinical Research Center, Fukuoka, 813-0017, Japan.
  • Maeda K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
  • Irie S; Fukuoka Mirai Hospital Clinical Research Center, Fukuoka, 813-0017, Japan.
  • Ieiri I; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
  • Sugiyama Y; Sugiyama Lab, RIKEN Innovation Center, RIKEN, Yokohama, Japan.
  • Kusuhara H; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan. Electronic address: kusuhara@mol.f.u-tokyo.ac.jp.
Drug Metab Pharmacokinet ; 34(1): 78-86, 2019 Feb.
Article en En | MEDLINE | ID: mdl-30528195
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Transportador 1 de Anión Orgánico Específico del Hígado / Genotipo Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Drug Metab Pharmacokinet Asunto de la revista: FARMACOLOGIA / METABOLISMO Año: 2019 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Transportador 1 de Anión Orgánico Específico del Hígado / Genotipo Tipo de estudio: Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Drug Metab Pharmacokinet Asunto de la revista: FARMACOLOGIA / METABOLISMO Año: 2019 Tipo del documento: Article País de afiliación: Japón