Type I interferon receptor blockade with anifrolumab corrects innate and adaptive immune perturbations of SLE.

Casey, Kerry A; Guo, Xiang; Smith, Michael A; Wang, Shiliang; Sinibaldi, Dominic; Sanjuan, Miguel A; Wang, Liangwei; Illei, Gabor G; White, Wendy I

Casey, Kerry A; Guo, Xiang; Smith, Michael A; Wang, Shiliang; Sinibaldi, Dominic; Sanjuan, Miguel A; Wang, Liangwei; Illei, Gabor G; White, Wendy I.

Afiliación

Casey KA; Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
Guo X; Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, USA.
Smith MA; Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
Wang S; Translational Sciences, MedImmune LLC, Gaithersburg, Maryland, USA.
Sinibaldi D; Research Bioinformatics, MedImmune LLC, Gaithersburg, Maryland, USA.
Sanjuan MA; Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland, USA.
Wang L; Biostatistics, MedImmune LLC, Gaithersburg, Maryland, USA.
Illei GG; Clinical Development, MedImmune LLC, Gaithersburg, Maryland, USA.
White WI; Research Bioinformatics, MedImmune LLC, Gaithersburg, Maryland, USA.

Lupus Sci Med ; 5(1): e000286, 2018.

Article en En | MEDLINE | ID: mdl-30538817

Palabras clave

disease activity; monoclonal antibody; systemic lupus erythematosus; type I interferon

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Lupus Sci Med Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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