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Efficacy of Ruxolitinib Therapy in a Patient With Severe Enterocolitis Associated With a STAT3 Gain-of-Function Mutation.
Parlato, Marianna; Charbit-Henrion, Fabienne; Abi Nader, Elie; Begue, Bernadette; Guegan, Nicolas; Bruneau, Julie; Khater, Shérine; Macintyre, Elizabeth; Picard, Capucine; Frédéric, Rieux-Laucat; Le Bourhis, Lionel; Allez, Matthieu; Goulet, Olivier; Cellier, Christophe; Hermine, Olivier; Cerf-Bensussan, Nadine; Malamut, Georgia.
Afiliación
  • Parlato M; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France.
  • Charbit-Henrion F; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France.
  • Abi Nader E; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France.
  • Begue B; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
  • Guegan N; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
  • Bruneau J; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France; AP-HP, Pathology, Hôpital Necker-Enfants Malades, Paris, France.
  • Khater S; AP-HP, Gastroenterology Hôpital Européen Georges Pompidou, Paris, France.
  • Macintyre E; Biological Hematology, Hôpital Necker Enfants Malades, Paris, France.
  • Picard C; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Study Center of Primary Immunodeficiency, Hôpital Necker-Enfants Malades, Paris, France.
  • Frédéric RL; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Inserm UMR1163, Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Paris, France.
  • Le Bourhis L; Inserm UMR 1160, Paris, France.
  • Allez M; Inserm UMR 1160, Paris, France; AP-HP Gastroenterology Hôpital Saint Louis, Université Paris, Diderot, France.
  • Goulet O; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Assistance Publique des Hôpitaux de Paris (AP-HP), Pediatric Gastroenterology, Hôpital Necker-Enfants Malades, Paris, France; AP-HP, Pathology, Hôpital Necker-Enfants Malades, Paris, France.
  • Cellier C; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Gastroenterology Hôpital Européen Georges Pompidou, Paris, France.
  • Hermine O; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Hematology, Hôpital Necker Enfants Malades, Paris, France.
  • Cerf-Bensussan N; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France. Electronic address: nadine.cerf-bensussan@inserm.fr.
  • Malamut G; Inserm UMR1163, Intestinal Immunity, Institut Imagine, Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; AP-HP, Gastroenterology, Hôpital Cochin, Paris, France. Electronic address: georgia.malamut@aphp.fr.
Gastroenterology ; 156(4): 1206-1210.e1, 2019 03.
Article en En | MEDLINE | ID: mdl-30557559
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_diarrhea / 3_neglected_diseases Asunto principal: Pirazoles / Inhibidores de Proteínas Quinasas / Enterocolitis / Factor de Transcripción STAT3 Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: Gastroenterology Año: 2019 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_diarrhea / 3_neglected_diseases Asunto principal: Pirazoles / Inhibidores de Proteínas Quinasas / Enterocolitis / Factor de Transcripción STAT3 Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Adult / Female / Humans Idioma: En Revista: Gastroenterology Año: 2019 Tipo del documento: Article País de afiliación: Francia