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High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1.
Liao, Lili; Alicea-Velázquez, Nilda L; Langbein, Lauren; Niu, Xiaohua; Cai, Weijia; Cho, Eun-Ah; Zhang, Meiling; Greer, Celeste B; Yan, Qin; Cosgrove, Michael S; Yang, Haifeng.
Afiliación
  • Liao L; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Alicea-Velázquez NL; Department of Pathology, Yale University, New Haven, CT, USA.
  • Langbein L; Department of Biochemistry and Molecular Biology, State University of New York Upstate Medical University, Syracuse, NY, USA.
  • Niu X; Department of Chemistry and Biochemistry, Central Connecticut State University, New Britain, CT, USA.
  • Cai W; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Cho EA; Department of Gastrointestinal Surgery, The Sixth Affiliated Hospital of Guangzhou Medical University, China.
  • Zhang M; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Greer CB; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Yan Q; Fox Chase Cancer Center, Philadelphia, PA, USA.
  • Cosgrove MS; Department of Pathology, Yale University, New Haven, CT, USA.
  • Yang H; Department of Pharmacology, Vanderbilt University, Nashville, TN, USA.
Mol Oncol ; 13(4): 811-828, 2019 04.
Article en En | MEDLINE | ID: mdl-30585695
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / Histonas / Proteínas Supresoras de Tumor / Lisina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / Histonas / Proteínas Supresoras de Tumor / Lisina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Oncol Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos