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Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy.
Kokkinaki, Dimitra; Hoffman, Matthew; Kalliora, Charikleia; Kyriazis, Ioannis D; Maning, Jennifer; Lucchese, Anna Maria; Shanmughapriya, Santhanam; Tomar, Dhanendra; Park, Joon Young; Wang, Hong; Yang, Xiao-Feng; Madesh, Muniswamy; Lymperopoulos, Anastasios; Koch, Walter J; Christofidou-Solomidou, Melpo; Drosatos, Konstantinos.
Afiliación
  • Kokkinaki D; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA; Faculty of Medicine, University of Crete, Voutes, Greece.
  • Hoffman M; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Kalliora C; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA; Faculty of Medicine, University of Crete, Voutes, Greece.
  • Kyriazis ID; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Maning J; Laboratory for the Study of Neurohormonal Control of the Circulation, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL, USA.
  • Lucchese AM; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Shanmughapriya S; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Tomar D; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Park JY; Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Wang H; Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA; Center for Metabolic Disease Research, Department of Pharmacology Lewis Katz School of Medicine, Temple University, 3500 Broad Street, Philadelphia, PA 19140, USA.
  • Yang XF; Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA; Center for Metabolic Disease Research, Department of Pharmacology Lewis Katz School of Medicine, Temple University, 3500 Broad Street, Philadelphia, PA 19140, USA.
  • Madesh M; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Lymperopoulos A; Laboratory for the Study of Neurohormonal Control of the Circulation, Nova Southeastern University College of Pharmacy, Fort Lauderdale, FL, USA.
  • Koch WJ; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
  • Christofidou-Solomidou M; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania Perelman School of Medicine, USA.
  • Drosatos K; Center for Translational Medicine and Department of Pharmacology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. Electronic address: drosatos@temple.edu.
J Mol Cell Cardiol ; 127: 232-245, 2019 02.
Article en En | MEDLINE | ID: mdl-30611795
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de salud: 4_sepsis / 6_cardiovascular_diseases / 6_other_circulatory_diseases Asunto principal: Butileno Glicoles / Sepsis / Miocitos Cardíacos / Glucósidos / Mitocondrias Cardíacas / Cardiomiopatías Tipo de estudio: Prognostic_studies Idioma: En Revista: J Mol Cell Cardiol Año: 2019 Tipo del documento: Article País de afiliación: Grecia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de salud: 4_sepsis / 6_cardiovascular_diseases / 6_other_circulatory_diseases Asunto principal: Butileno Glicoles / Sepsis / Miocitos Cardíacos / Glucósidos / Mitocondrias Cardíacas / Cardiomiopatías Tipo de estudio: Prognostic_studies Idioma: En Revista: J Mol Cell Cardiol Año: 2019 Tipo del documento: Article País de afiliación: Grecia