Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO<sub>4</sub> recognition and ADP-ribosylation.

Banerjee, Ankan; Munir, Annum; Abdullahu, Leonora; Damha, Masad J; Goldgur, Yehuda; Shuman, Stewart

Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO₄ recognition and ADP-ribosylation.

Banerjee, Ankan; Munir, Annum; Abdullahu, Leonora; Damha, Masad J; Goldgur, Yehuda; Shuman, Stewart.

Afiliación

Banerjee A; Molecular Biology and Structural Biology Programs, Sloan-Kettering Institute, New York, NY, 10065, USA.
Munir A; Molecular Biology and Structural Biology Programs, Sloan-Kettering Institute, New York, NY, 10065, USA.
Abdullahu L; Chemistry Department, McGill University, Montreal, Quebec, H3A0B8, Canada.
Damha MJ; Chemistry Department, McGill University, Montreal, Quebec, H3A0B8, Canada.
Goldgur Y; Molecular Biology and Structural Biology Programs, Sloan-Kettering Institute, New York, NY, 10065, USA.
Shuman S; Molecular Biology and Structural Biology Programs, Sloan-Kettering Institute, New York, NY, 10065, USA. s-shuman@ski.mskcc.org.

Nat Commun ; 10(1): 218, 2019 01 15.

Article en En | MEDLINE | ID: mdl-30644400

Asunto(s)

Proteínas Bacterianas/metabolismo; Clostridium thermocellum/enzimología; ARN de Transferencia/metabolismo; Adenosina Difosfato Ribosa/análogos & derivados; Adenosina Difosfato Ribosa/metabolismo; Secuencia de Aminoácidos; Proteínas Bacterianas/química; Ligandos; NAD/metabolismo; Fosfatos/metabolismo; Conformación Proteica

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / ARN de Transferencia / Clostridium thermocellum Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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