O-GlcNAc transferase activates stem-like cell potential in hepatocarcinoma through O-GlcNAcylation of eukaryotic initiation factor 4E.

Cao, Benjin; Duan, Meng; Xing, Yang; Liu, Chanjuan; Yang, Fan; Li, Yinan; Yang, Tianxiao; Wei, Yuanyan; Gao, Qiang; Jiang, Jianhai

Cao, Benjin; Duan, Meng; Xing, Yang; Liu, Chanjuan; Yang, Fan; Li, Yinan; Yang, Tianxiao; Wei, Yuanyan; Gao, Qiang; Jiang, Jianhai.

Afiliación

Cao B; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Duan M; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China.
Xing Y; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Liu C; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Yang F; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Li Y; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Yang T; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Wei Y; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.
Gao Q; Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China.
Jiang J; Key Laboratory of Glycoconjuates Research, Ministry of Public Health, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan, Shanghai, People's Republic of China.

J Cell Mol Med ; 23(4): 2384-2398, 2019 04.

Article en En | MEDLINE | ID: mdl-30677218

Asunto(s)

Carcinoma Hepatocelular/genética; Factor 4E Eucariótico de Iniciación/genética; Neoplasias Hepáticas/genética; N-Acetilglucosaminiltransferasas/genética; Acilación/genética; Anciano; Apoptosis/genética; Carcinoma Hepatocelular/patología; Proliferación Celular/genética; Supervivencia sin Enfermedad; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Glucosa/metabolismo; Humanos; Neoplasias Hepáticas/patología; Masculino; Persona de Mediana Edad; Células Madre Neoplásicas/patología; Pronóstico; Procesamiento Proteico-Postraduccional/genética; ARN Interferente Pequeño/genética; Transducción de Señal/genética

Palabras clave

O-GlcNAc transferase; O-GlcNAcylation; eukaryotic initiation factor 4E; hepatocellular carcinoma; stem-like cell potential

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: N-Acetilglucosaminiltransferasas / Carcinoma Hepatocelular / Factor 4E Eucariótico de Iniciación / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2019 Tipo del documento: Article

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