New p-terphenyl and benzoquinone metabolites from the bioluminescent mushroom Neonothopanus nambi.
Nat Prod Res
; 34(15): 2186-2193, 2020 Aug.
Article
en En
| MEDLINE
| ID: mdl-30810369
ABSTRACT
Two new p-terphenyls, neonambiterphenyls A and B (1-2), a new benzoquinone, neonambiquinone A (3), together with six known sesquiterpenes (4-9), were isolated from the bioluminescent mushroom Neonothopanus nambi PW3. The isolated compounds were identified by mass, IR and spectroscopic analyses (1D and 2D NMR). Compounds 1-3 and 5-7 showed cytotoxicity against cancer cell lines such as KB, NCI-H187 and MCF-7 with IC50 values ranging from 1.45 to 49.31 µg/mL. In addition, compounds 1 and 5 showed cytotoxicity against Vero cells with IC50 values of 38.72 and 32.90 µg/mL, respectively.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sesquiterpenos
/
Benzoquinonas
/
Agaricales
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Prod Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Tailandia