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A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation.
Gutierrez, Denisse A; DeJesus, Rebecca E; Contreras, Lisett; Rodriguez-Palomares, Isela A; Villanueva, Paulina J; Balderrama, Karol S; Monterroza, Lenore; Larragoity, Manuel; Varela-Ramirez, Armando; Aguilera, Renato J.
Afiliación
  • Gutierrez DA; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • DeJesus RE; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Contreras L; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Rodriguez-Palomares IA; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Villanueva PJ; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Balderrama KS; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Monterroza L; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Larragoity M; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Varela-Ramirez A; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA.
  • Aguilera RJ; The Cytometry, Screening, and Imaging Core Facility, Border Biomedical Research Center, Department of Biological Sciences, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX, 79968-0519, USA. raguilera@utep.edu.
Cell Biol Toxicol ; 35(6): 503-519, 2019 12.
Article en En | MEDLINE | ID: mdl-30825052
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: Cell Biol Toxicol Asunto de la revista: TOXICOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridazinas / Neoplasias / Antineoplásicos Límite: Humans Idioma: En Revista: Cell Biol Toxicol Asunto de la revista: TOXICOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos