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Compounds based on 5-(perylen-3-ylethynyl)uracil scaffold: High activity against tick-borne encephalitis virus and non-specific activity against enterovirus A.
Chistov, Alexey A; Orlov, Alexey A; Streshnev, Philipp P; Slesarchuk, Nikita A; Aparin, Ilya O; Rathi, Brijesh; Brylev, Vladimir A; Kutyakov, Sergey V; Mikhura, Irina V; Ustinov, Alexey V; Westman, Gunnar; Palyulin, Vladimir A; Jain, Nidhi; Osolodkin, Dmitry I; Kozlovskaya, Liubov I; Korshun, Vladimir A.
Afiliación
  • Chistov AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Orlov AA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia; FSBSI "Chumakov FSC R&D IBP RAS", 8 bd 1 Poselok Instituta Poliomielita, Poselenie Moskovsky, Moscow 108819, Russia; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory
  • Streshnev PP; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Slesarchuk NA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Aparin IO; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia; Skolkovo Institute of Science and Technology, Skolkovo, Moscow 143026, Russia.
  • Rathi B; Department of Chemistry, Laboratory for Translational Chemistry and Drug Discovery, Hansraj College University Enclave, University of Delhi, Delhi 110007, India.
  • Brylev VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia; Biotech Innovations Ltd, Leninskie gory 1 bd 75, Moscow 119992, Russia.
  • Kutyakov SV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Mikhura IV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Ustinov AV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
  • Westman G; Chalmers University of Technology, SE-412 96, Gothenburg, Sweden.
  • Palyulin VA; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 1 bd 3, Moscow 119992, Russia.
  • Jain N; Department of Chemistry, Indian Institute of Technology, Delhi, India.
  • Osolodkin DI; FSBSI "Chumakov FSC R&D IBP RAS", 8 bd 1 Poselok Instituta Poliomielita, Poselenie Moskovsky, Moscow 108819, Russia; Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 1 bd 3, Moscow 119992, Russia; Sechenov First Moscow State Medical University, Moscow 119991, Russia.
  • Kozlovskaya LI; FSBSI "Chumakov FSC R&D IBP RAS", 8 bd 1 Poselok Instituta Poliomielita, Poselenie Moskovsky, Moscow 108819, Russia; Sechenov First Moscow State Medical University, Moscow 119991, Russia. Electronic address: lubov_i_k@mail.ru.
  • Korshun VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia. Electronic address: korshun@ibch.ru.
Eur J Med Chem ; 171: 93-103, 2019 Jun 01.
Article en En | MEDLINE | ID: mdl-30909022
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Uracilo / Barrera Hematoencefálica / Enterovirus Humano A / Virus de la Encefalitis Transmitidos por Garrapatas Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Uracilo / Barrera Hematoencefálica / Enterovirus Humano A / Virus de la Encefalitis Transmitidos por Garrapatas Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: Rusia