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Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883).
Hauke, Jan; Hahnen, Eric; Schneider, Stephanie; Reuss, Alexander; Richters, Lisa; Kommoss, Stefan; Heimbach, André; Marmé, Frederik; Schmidt, Sandra; Prieske, Katharina; Gevensleben, Heidrun; Burges, Alexander; Borde, Julika; De Gregorio, Nikolaus; Nürnberg, Peter; El-Balat, Ahmed; Thiele, Holger; Hilpert, Felix; Altmüller, Janine; Meier, Werner; Dietrich, Dimo; Kimmig, Rainer; Schoemig-Markiefka, Birgid; Kast, Karin; Braicu, Elena; Baumann, Klaus; Jackisch, Christian; Park-Simon, Tjoung-Won; Ernst, Corinna; Hanker, Lars; Pfisterer, Jacobus; Schnelzer, Andreas; du Bois, Andreas; Schmutzler, Rita K; Harter, Philipp.
Afiliación
  • Hauke J; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Hahnen E; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany eric.hahnen@uk-koeln.de.
  • Schneider S; Department of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte Evangelische Huyssens-Stiftung/Knappschaft GmbH, Essen, Germany.
  • Reuss A; Coordinating Center for Clinical Trials, Philipps-University of Marburg, Marburg, Germany.
  • Richters L; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Kommoss S; Department of Women's Health, University Hospital Tuebingen, Tuebingen, Germany.
  • Heimbach A; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.
  • Marmé F; National Center for Tumor Disease, Department of Gynecology, University of Heidelberg, Heidelberg, Germany.
  • Schmidt S; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • Prieske K; Department of Gynecology and Gynecologic Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Gevensleben H; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
  • Burges A; Department of Gynecology, University Hospital Munich-Großhadern, Munich, Germany.
  • Borde J; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
  • De Gregorio N; Department of Gynecology and Obstetrics, University Hospital, Universität Ulm, Ulm, Germany.
  • Nürnberg P; Cologne Center for Genomics (CCG) & Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • El-Balat A; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Thiele H; Department of Gynecology, University of Frankfurt, Frankfurt, Germany.
  • Hilpert F; Cologne Center for Genomics (CCG) & Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Altmüller J; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
  • Meier W; Department of Gynecology, University of Kiel, Kiel, Germany.
  • Dietrich D; Onkologisches Therapiezentrum, Krankenhaus Jerusalem, Hamburg, Germany.
  • Kimmig R; Cologne Center for Genomics (CCG) & Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Schoemig-Markiefka B; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
  • Kast K; Department of Gynecology and Obstetrics, University Hospital Duesseldorf, Duesseldorf, Germany.
  • Braicu E; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Germany.
  • Baumann K; Department of Gynecology, University of Essen, Essen, Germany.
  • Jackisch C; Institute of Pathology, University Hospital Cologne, Cologne, Germany.
  • Park-Simon TW; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Ernst C; German Cancer Consortium (DKTK), Dresden and German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT), Partner Site Dresden, Heidelberg, Germany.
  • Hanker L; Department of Gynecology and Gynecological Oncology, Charité, Berlin, Germany.
  • Pfisterer J; Department of Gynecology, Gynecologic Endocrinology and Oncology, University of Gießen and Marburg GmbH, Marburg, Germany.
  • Schnelzer A; Department of Gynecology and Obstetrics, Klinikum Ludwigshafen, Ludwigshafen, Germany.
  • du Bois A; Department of Gynecology and Obstetrics, Sana Klinikum, Offenbach, Germany.
  • Schmutzler RK; Department of Gynecology, Hannover Medical School, Hannover, Germany.
  • Harter P; Center for Hereditary Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), Medical Faculty, University Hospital Cologne, Cologne, Germany.
J Med Genet ; 56(9): 574-580, 2019 09.
Article en En | MEDLINE | ID: mdl-30979843
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Neoplasias Ováricas / Eliminación de Secuencia / Predisposición Genética a la Enfermedad / Estudios de Asociación Genética Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: J Med Genet Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Neoplasias Ováricas / Eliminación de Secuencia / Predisposición Genética a la Enfermedad / Estudios de Asociación Genética Tipo de estudio: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: J Med Genet Año: 2019 Tipo del documento: Article País de afiliación: Alemania