Genetic diversity and structural analysis of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) from <i>Plasmodium falciparum</i>.

Kadian, Kavita; Vijay, Sonam; Rawal, Ritu; Singh, Jagbir; Anvikar, Anup; Pande, Veena; Sharma, Arun

Genetic diversity and structural analysis of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) from Plasmodium falciparum.

Kadian, Kavita; Vijay, Sonam; Rawal, Ritu; Singh, Jagbir; Anvikar, Anup; Pande, Veena; Sharma, Arun.

Afiliación

Kadian K; Protein Biochemistry and Structural Biology Laboratory, ICMR-National Institute of Malaria Research, New Delhi, India.
Vijay S; Protein Biochemistry and Structural Biology Laboratory, ICMR-National Institute of Malaria Research, New Delhi, India.
Rawal R; Protein Biochemistry and Structural Biology Laboratory, ICMR-National Institute of Malaria Research, New Delhi, India.
Singh J; Protein Biochemistry and Structural Biology Laboratory, ICMR-National Institute of Malaria Research, New Delhi, India.
Anvikar A; Epidemiology and Clinical Research Division, ICMR-National Institute of Malaria Research, New Delhi, India.
Pande V; Department of Biotechnology, Kumaun University, Nainital, Uttarakhand, India.
Sharma A; Protein Biochemistry and Structural Biology Laboratory, ICMR-National Institute of Malaria Research, New Delhi, India.

J Vector Borne Dis ; 55(4): 271-281, 2018.

Article en En | MEDLINE | ID: mdl-30997887

Asunto(s)

Fosfotransferasas (Aceptor de Grupo Alcohol)/química; Filogenia; Plasmodium falciparum/enzimología; Plasmodium falciparum/genética; Proteínas Protozoarias/química; Dominio Catalítico; Eritritol/análogos & derivados; Eritritol/química; Eritritol/genética; Variación Genética; India; Modelos Moleculares; Fosfotransferasas (Aceptor de Grupo Alcohol)/genética; Proteínas Protozoarias/genética; Análisis de Secuencia de ADN; Terpenos/metabolismo

Palabras clave

4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE); Plasmodium falciparum; gene; genetic diversity; methylerythritol phosphate (MEP) pathway; molecular modeling; phylogenetic analysis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_malaria Asunto principal: Filogenia / Plasmodium falciparum / Proteínas Protozoarias / Fosfotransferasas (Aceptor de Grupo Alcohol) País/Región como asunto: Asia Idioma: En Revista: J Vector Borne Dis Asunto de la revista: MEDICINA TROPICAL / PARASITOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: India

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