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Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection.
Dubois, Hanne; Sorgeloos, Frederic; Sarvestani, Soroush T; Martens, Liesbet; Saeys, Yvan; Mackenzie, Jason M; Lamkanfi, Mohamed; van Loo, Geert; Goodfellow, Ian; Wullaert, Andy.
Afiliación
  • Dubois H; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
  • Sorgeloos F; VIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
  • Sarvestani ST; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
  • Martens L; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
  • Saeys Y; VIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
  • Mackenzie JM; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
  • Lamkanfi M; VIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
  • van Loo G; Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
  • Goodfellow I; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
  • Wullaert A; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
PLoS Pathog ; 15(4): e1007709, 2019 04.
Article en En | MEDLINE | ID: mdl-31017981
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_zoonosis Asunto principal: Infecciones por Caliciviridae / Tracto Gastrointestinal / Factor de Transcripción STAT1 / Proteínas Reguladoras de la Apoptosis / Inflamasomas / Piroptosis / Proteína con Dominio Pirina 3 de la Familia NLR Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2019 Tipo del documento: Article País de afiliación: Bélgica
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_neglected_diseases / 3_zoonosis Asunto principal: Infecciones por Caliciviridae / Tracto Gastrointestinal / Factor de Transcripción STAT1 / Proteínas Reguladoras de la Apoptosis / Inflamasomas / Piroptosis / Proteína con Dominio Pirina 3 de la Familia NLR Límite: Animals Idioma: En Revista: PLoS Pathog Año: 2019 Tipo del documento: Article País de afiliación: Bélgica