Is sex associated with adverse outcomes after percutaneous coronary intervention for CTO?
Int J Cardiol
; 288: 29-33, 2019 08 01.
Article
en En
| MEDLINE
| ID: mdl-31047703
ABSTRACT
BACKGROUND:
Conflicting results have been reported regarding sex differences in percutaneous coronary intervention (PCI), but their potential influence on clinical outcomes after chronic total coronary occlusion (CTO) PCI remains unknown. We aimed to identify sex-related differences in long-term clinical outcomes after CTO PCI. METHODS ANDRESULTS:
All consecutive patients undergoing CTO PCI between 2004 and 2012 were included in a prospective registry. Baseline, procedural characteristics and clinical outcomes were compared according to sex. Out of 1343 patients, 194 were female (14.4%). Women were older (68.5⯱â¯9.9 vs 62.3⯱â¯10.8â¯years, pâ¯<â¯0.001), more frequently diabetic (33.5% vs 26.4%, pâ¯=â¯0.026) and hypertensive (70.1% vs 57.4%, pâ¯<â¯0,001), whereas males were more frequently smokers (28.5% vs 15.5%, pâ¯<â¯0.001). J-CTO score was similar between both sexes (1.59⯱â¯0.91 vs 1.51⯱â¯0.88). The procedural success rate was also similar in men and women (74.0% vs 77.3%, respectively). At 8â¯years' follow-up, successful CTO PCI was associated with reduced mortality in women (14.8% vs 36.2%, pâ¯=â¯0.003) and men (18.5% vs 29.1%, pâ¯<â¯0.001). In successful CTO PCI cases, no sex-related differences were observed in terms of major adverse cardiac events.CONCLUSIONS:
Our study suggests an equal benefit of CTO interventions with a marked reduction in mortality after successful CTO PCI in women and men alike.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
6_cardiovascular_diseases
/
6_ischemic_heart_disease
Asunto principal:
Sistema de Registros
/
Medición de Riesgo
/
Oclusión Coronaria
/
Intervención Coronaria Percutánea
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Int J Cardiol
Año:
2019
Tipo del documento:
Article
País de afiliación:
Francia