Interleukin-1beta Inhibition Attenuates Vasculitis in a Mouse Model of Kawasaki Disease.

Hashimoto, Yoshiaki; Fukazawa, Ryuji; Nagi-Miura, Noriko; Ohno, Naohito; Suzuki, Nobuko; Katsube, Yasuhiro; Kamisago, Mitsuhiro; Akao, Miharu; Watanabe, Makoto; Hashimoto, Koji; Tsuno, Kanae; Matsui, Ryosuke; Itoh, Yasuhiko

Hashimoto, Yoshiaki; Fukazawa, Ryuji; Nagi-Miura, Noriko; Ohno, Naohito; Suzuki, Nobuko; Katsube, Yasuhiro; Kamisago, Mitsuhiro; Akao, Miharu; Watanabe, Makoto; Hashimoto, Koji; Tsuno, Kanae; Matsui, Ryosuke; Itoh, Yasuhiko.

Afiliación

Hashimoto Y; Department of Pediatrics, Nippon Medical School.
Fukazawa R; Department of Pediatrics, Nippon Medical School.
Nagi-Miura N; Laboratory for Immunopharmacology of Microbial Products, Tokyo University of Pharmacy and Life Sciences.
Ohno N; Laboratory for Immunopharmacology of Microbial Products, Tokyo University of Pharmacy and Life Sciences.
Suzuki N; Department of Pediatrics, Nippon Medical School.
Katsube Y; Department of Pediatrics, Nippon Medical School.
Kamisago M; Department of Pediatrics, Nippon Medical School.
Akao M; Department of Pediatrics, Nippon Medical School.
Watanabe M; Department of Pediatrics, Nippon Medical School.
Hashimoto K; Department of Pediatrics, Nippon Medical School.
Tsuno K; Department of Pediatrics, Nippon Medical School.
Matsui R; Department of Pediatrics, Nippon Medical School.
Itoh Y; Department of Pediatrics, Nippon Medical School.

J Nippon Med Sch ; 86(2): 108-116, 2019.

Article en En | MEDLINE | ID: mdl-31130561

Asunto(s)

Anticuerpos/administración & dosificación; Interleucina-1beta/inmunología; Interleucina-1beta/metabolismo; Síndrome Mucocutáneo Linfonodular/tratamiento farmacológico; Síndrome Mucocutáneo Linfonodular/inmunología; Animales; Anticuerpos/farmacología; Aorta/patología; Modelos Animales de Enfermedad; Inmunidad Innata; Interleucina-10/metabolismo; Interleucina-6/metabolismo; Masculino; Ratones Endogámicos DBA; Síndrome Mucocutáneo Linfonodular/patología; Transducción de Señal/efectos de los fármacos; Transducción de Señal/inmunología; Factores de Tiempo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Kawasaki disease; Kawasaki disease model mouse; cytokine profile; interleukin-10; interleukin-1beta

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interleucina-1beta / Anticuerpos / Síndrome Mucocutáneo Linfonodular Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Nippon Med Sch Asunto de la revista: MEDICINA Año: 2019 Tipo del documento: Article

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