The novel polyclonal Ab preparation trimodulin attenuates <i>ex vivo</i> endotoxin-induced immune reactions in early hyperinflammation.

Duerr, Celia; Bacher, Annica; de Martin, Angelika; Sachet, Monika; Sadeghi, Kambis; Baumann, Suzann; Heinz, Corina; Spittler, Andreas

The novel polyclonal Ab preparation trimodulin attenuates ex vivo endotoxin-induced immune reactions in early hyperinflammation.

Duerr, Celia; Bacher, Annica; de Martin, Angelika; Sachet, Monika; Sadeghi, Kambis; Baumann, Suzann; Heinz, Corina; Spittler, Andreas.

Afiliación

Duerr C; 1 Department of Surgery, Research Laboratories, Medical University of Vienna, Vienna, Austria.
Bacher A; 2 Department of Paediatrics, Medical University of Vienna, Austria.
de Martin A; 3 Department of Surgery, University Hospital St. Pölten, Karl Landsteiner Private University for Health Sciences, Austria.
Sachet M; 1 Department of Surgery, Research Laboratories, Medical University of Vienna, Vienna, Austria.
Sadeghi K; 1 Department of Surgery, Research Laboratories, Medical University of Vienna, Vienna, Austria.
Baumann S; 2 Department of Paediatrics, Medical University of Vienna, Austria.
Heinz C; 1 Department of Surgery, Research Laboratories, Medical University of Vienna, Vienna, Austria.
Spittler A; 4 Department of Preclinical Research - Translational Research, Biotest AG, Dreieich, Germany.

Innate Immun ; 25(6): 374-388, 2019 08.

Article en En | MEDLINE | ID: mdl-31165655

Asunto(s)

Anticuerpos/metabolismo; Mezclas Complejas/metabolismo; Inflamación/inmunología; Monocitos/inmunología; Sepsis/tratamiento farmacológico; Adulto; Anciano; Antígeno CD11b/metabolismo; Células Cultivadas; Femenino; Voluntarios Sanos; Humanos; Inmunoglobulina A/sangre; Inmunoglobulina G/sangre; Inmunoglobulina M/sangre; Inmunomodulación; Lipopolisacáridos/inmunología; Masculino; Persona de Mediana Edad; Receptores de IgG/metabolismo; Ácidos Teicoicos/inmunología; Receptor Toll-Like 2/metabolismo; Receptor Toll-Like 4/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Cytokines; Ig; inflammatory response; monocytes; sepsis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monocitos / Sepsis / Mezclas Complejas / Inflamación / Anticuerpos Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Innate Immun Asunto de la revista: ALERGIA E IMUNOLOGIA / BACTERIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Austria

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