Intracranial acute promyelocytic leukemia at presentation-A case-based discussion.
Leuk Res Rep
; 11: 41-45, 2019.
Article
en En
| MEDLINE
| ID: mdl-31193772
ABSTRACT
Intracranial disease is a very rare presentation at diagnosis in acute promyelocytic leukemia (APL). The risk associated with this particular presentation is not accounted for when the current risk stratification is based on peripheral counts. Extra medullary disease in general may challenge this risk stratification that commands initial induction treatment of this potentially fatal disease. Here we discuss a case presented at diagnosis with extensive intracranial base of the skull, clivus and sinus infiltration and heavily infiltrated bone marrow yet with low peripheral blood counts and no peripheral blood blasts. Such cases lack evidence of how to treat.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Leuk Res Rep
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos