Naphthalene-benzoindole derived two novel fluorometric pH-Responsive probes for environmental systems and bioimaging.
Talanta
; 203: 90-98, 2019 Oct 01.
Article
en En
| MEDLINE
| ID: mdl-31202355
ABSTRACT
In this work, we designed a kind of novel fluorescent probes based on naphthalene-benzoindole conjugate derived for sensitively monitoring the pH fluctuation in environment and biological systems. In the spectral method, these two probes both show significant red shift, color change and fluorescence quenching due to the effect of intramolecular charge transfer (ICT) mechanism. Moreover, we found that the probe bearing with carboxyl group displayed a more hydrophilicity than the one bearing with hydrogen atom instead, and the former exhibits a faster response and higher fluorescence intensity. Besides, the probe bearing with carboxyl group shows lower cytotoxicity, evidences by the vitro study. It indicates that this probe has great potential in application in living cell imaging as well as pH-fluctuation monitoring.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Colorantes Fluorescentes
/
Indoles
/
Naftalenos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Talanta
Año:
2019
Tipo del documento:
Article
País de afiliación:
China