Your browser doesn't support javascript.
loading
Genetic basis of ruminant headgear and rapid antler regeneration.
Wang, Yu; Zhang, Chenzhou; Wang, Nini; Li, Zhipeng; Heller, Rasmus; Liu, Rong; Zhao, Yue; Han, Jiangang; Pan, Xiangyu; Zheng, Zhuqing; Dai, Xueqin; Chen, Ceshi; Dou, Mingle; Peng, Shujun; Chen, Xianqing; Liu, Jing; Li, Ming; Wang, Kun; Liu, Chang; Lin, Zeshan; Chen, Lei; Hao, Fei; Zhu, Wenbo; Song, Chengchuang; Zhao, Chen; Zheng, Chengli; Wang, Jianming; Hu, Shengwei; Li, Cunyuan; Yang, Hui; Jiang, Lin; Li, Guangyu; Liu, Mingjun; Sonstegard, Tad S; Zhang, Guojie; Jiang, Yu; Wang, Wen; Qiu, Qiang.
Afiliación
  • Wang Y; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Zhang C; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Wang N; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Li Z; Department of Special Animal Nutrition and Feed Science, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China.
  • Heller R; Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, DK-2100 Copenhagen, Denmark.
  • Liu R; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.
  • Zhao Y; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China.
  • Han J; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Pan X; Institute of Animal Science (IAS), Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
  • Zheng Z; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Dai X; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Chen C; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.
  • Dou M; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China.
  • Peng S; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.
  • Chen X; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China.
  • Liu J; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Li M; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Wang K; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Liu C; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Lin Z; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Chen L; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Hao F; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Zhu W; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Song C; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Zhao C; Center of Special Environmental Biomechanics and Biomedical Engineering, School of Life Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Zheng C; Center for Ecological and Environmental Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Wang J; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Hu S; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, China.
  • Li C; Sichuan Institute of Musk Deer Breeding, Sichuan 610000, China.
  • Yang H; Sichuan Institute of Musk Deer Breeding, Sichuan 610000, China.
  • Jiang L; College of Life Sciences, Shihezi University, Shihezi, Xinjiang 832003, China.
  • Li G; College of Life Sciences, Shihezi University, Shihezi, Xinjiang 832003, China.
  • Liu M; Center of Special Environmental Biomechanics and Biomedical Engineering, School of Life Sciences, Northwestern Polytechnical University, Xi'an 710072, China.
  • Sonstegard TS; Institute of Animal Science (IAS), Chinese Academy of Agricultural Sciences (CAAS), Beijing 100193, China.
  • Zhang G; Department of Special Animal Nutrition and Feed Science, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China.
  • Jiang Y; The Key Laboratory of Animal Biotechnology of Xinjiang, Xinjiang Academy of Animal Science, Xinjiang, Urumqi 830026, China.
  • Wang W; Recombinetics, Inc., St. Paul, MN 55104, USA.
  • Qiu Q; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China.
Science ; 364(6446)2019 06 21.
Article en En | MEDLINE | ID: mdl-31221830
Ruminants are the only extant mammalian group possessing bony (osseous) headgear. We obtained 221 transcriptomes from bovids and cervids and sequenced three genomes representing the only two pecoran lineages that convergently lack headgear. Comparative analyses reveal that bovid horns and cervid antlers share similar gene expression profiles and a common cellular basis developed from neural crest stem cells. The rapid regenerative properties of antler tissue involve exploitation of oncogenetic pathways, and at the same time some tumor suppressor genes are under strong selection in deer. These results provide insights into the evolutionary origin of ruminant headgear as well as mammalian organ regeneration and oncogenesis.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuernos de Venado / Regeneración / Rumiantes Límite: Animals Idioma: En Revista: Science Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cuernos de Venado / Regeneración / Rumiantes Límite: Animals Idioma: En Revista: Science Año: 2019 Tipo del documento: Article País de afiliación: China