Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma.

Cao, Lan; Basudan, Ahmed; Sikora, Matthew J; Bahreini, Amir; Tasdemir, Nilgun; Levine, Kevin M; Jankowitz, Rachel C; McAuliffe, Priscilla F; Dabbs, David; Haupt, Sue; Haupt, Ygal; Lucas, Peter C; Lee, Adrian V; Oesterreich, Steffi; Atkinson, Jennifer M

Cao, Lan; Basudan, Ahmed; Sikora, Matthew J; Bahreini, Amir; Tasdemir, Nilgun; Levine, Kevin M; Jankowitz, Rachel C; McAuliffe, Priscilla F; Dabbs, David; Haupt, Sue; Haupt, Ygal; Lucas, Peter C; Lee, Adrian V; Oesterreich, Steffi; Atkinson, Jennifer M.

Afiliación

Cao L; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; Department of Obstetrics and Gynecology, The Third Xiangya Hospital, Central South University, Changsha, China; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Basudan A; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
Sikora MJ; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Bahreini A; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Tasdemir N; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology; University of Pittsburgh, Pittsburgh, PA, USA.
Levine KM; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Jankowitz RC; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Medicine, Division of Hematology Oncology; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
McAuliffe PF; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Division of Surgical Oncology, Department of Surgery, Pittsburgh, PA, USA.
Dabbs D; Division of Breast and Gynecologic Pathology, Department of Pathology, Pittsburgh, PA, USA.
Haupt S; Peter MacCallum Cancer Center, Melbourne, Australia.
Haupt Y; Peter MacCallum Cancer Center, Melbourne, Australia.
Lucas PC; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Lee AV; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology; University of
Oesterreich S; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology; University of Pittsburgh, Pittsburgh, PA, USA.
Atkinson JM; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA; UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Department of Pharmacology and Chemical Biology; University of Pittsburgh, Pittsburgh, PA, USA.

Cancer Lett ; 461: 21-30, 2019 Oct 01.

Article en En | MEDLINE | ID: mdl-31229512

Asunto(s)

Neoplasias de la Mama/patología; Carcinoma Lobular/patología; Proteínas de Ciclo Celular/genética; Receptor alfa de Estrógeno/genética; Amplificación de Genes; Recurrencia Local de Neoplasia/patología; Proteínas Proto-Oncogénicas/genética; Receptor ErbB-2/genética; Apoptosis; Biomarcadores de Tumor; Neoplasias de la Mama/genética; Neoplasias de la Mama/metabolismo; Carcinoma Ductal de Mama/genética; Carcinoma Ductal de Mama/metabolismo; Carcinoma Ductal de Mama/patología; Carcinoma Lobular/genética; Carcinoma Lobular/metabolismo; Puntos de Control del Ciclo Celular; Proteínas de Ciclo Celular/metabolismo; Proliferación Celular; Variaciones en el Número de Copia de ADN; Femenino; Estudios de Seguimiento; Regulación Neoplásica de la Expresión Génica; Humanos; Persona de Mediana Edad; Invasividad Neoplásica; Recurrencia Local de Neoplasia/genética; Recurrencia Local de Neoplasia/metabolismo; Pronóstico; Proteínas Proto-Oncogénicas/metabolismo; Estudios Retrospectivos; Tasa de Supervivencia; Células Tumorales Cultivadas; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

Amplification; ERBB2; ESR1; ILC; MDM4

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_breast_cancer Asunto principal: Neoplasias de la Mama / Amplificación de Genes / Proteínas Proto-Oncogénicas / Carcinoma Lobular / Receptor ErbB-2 / Proteínas de Ciclo Celular / Receptor alfa de Estrógeno / Recurrencia Local de Neoplasia Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Cancer Lett Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google