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Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT6.
Ali, Wesam; Wiecek, Malgorzata; Lazewska, Dorota; Kurczab, Rafal; Jastrzebska-Wiesek, Magdalena; Satala, Grzegorz; Kucwaj-Brysz, Katarzyna; Lubelska, Annamaria; Gluch-Lutwin, Monika; Mordyl, Barbara; Siwek, Agata; Nasim, Muhammad Jawad; Partyka, Anna; Sudol, Sylwia; Latacz, Gniewomir; Wesolowska, Anna; Kiec-Kononowicz, Katarzyna; Handzlik, Jadwiga.
Afiliación
  • Ali W; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland; Division of Bioorganic Chemistry, School of Pharmacy, University of Saarland, Campus B2 1, D-66123, Saarbruecken, Germany.
  • Wiecek M; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Lazewska D; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Kurczab R; Department of Medicinal Chemistry Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL, 31-343, Kraków, Poland.
  • Jastrzebska-Wiesek M; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Satala G; Department of Medicinal Chemistry Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL, 31-343, Kraków, Poland.
  • Kucwaj-Brysz K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Lubelska A; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Gluch-Lutwin M; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Mordyl B; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Siwek A; Department of Pharmacobiology, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Nasim MJ; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland; Division of Bioorganic Chemistry, School of Pharmacy, University of Saarland, Campus B2 1, D-66123, Saarbruecken, Germany.
  • Partyka A; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Sudol S; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Wesolowska A; Department of Clinical Pharmacy, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Kiec-Kononowicz K; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, PL, 30-688, Kraków, Poland. Electronic address: j.handzlik@uj.edu.pl.
Eur J Med Chem ; 178: 740-751, 2019 Sep 15.
Article en En | MEDLINE | ID: mdl-31229876
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas de la Serotonina / Procesamiento de Imagen Asistido por Computador / Receptores de Serotonina Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antagonistas de la Serotonina / Procesamiento de Imagen Asistido por Computador / Receptores de Serotonina Límite: Animals / Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article País de afiliación: Alemania