miR-330 suppresses EMT and induces apoptosis by downregulating HMGA2 in human colorectal cancer.

Mansoori, Behzad; Mohammadi, Ali; Naghizadeh, Sanaz; Gjerstorff, Morten; Shanehbandi, Dariush; Shirjang, Solmaz; Najafi, Souzan; Holmskov, Uffe; Khaze, Vahid; Duijf, Pascal H G; Baradaran, Behzad

Mansoori, Behzad; Mohammadi, Ali; Naghizadeh, Sanaz; Gjerstorff, Morten; Shanehbandi, Dariush; Shirjang, Solmaz; Najafi, Souzan; Holmskov, Uffe; Khaze, Vahid; Duijf, Pascal H G; Baradaran, Behzad.

Afiliación

Mansoori B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammadi A; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Naghizadeh S; Aging Research Institute, Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Gjerstorff M; Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Shanehbandi D; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Shirjang S; Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Najafi S; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Holmskov U; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khaze V; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Duijf PHG; Department of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Baradaran B; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

J Cell Physiol ; 235(2): 920-931, 2020 02.

Article en En | MEDLINE | ID: mdl-31241772

Asunto(s)

Apoptosis/genética; Neoplasias Colorrectales/patología; Transición Epitelial-Mesenquimal/genética; Proteína HMGA2/metabolismo; MicroARNs/genética; Antígenos CD/metabolismo; Cadherinas/metabolismo; Línea Celular Tumoral; Movimiento Celular/genética; Proliferación Celular/genética; Neoplasias Colorrectales/genética; Regulación Neoplásica de la Expresión Génica/genética; Genes Supresores de Tumor; Células HCT116; Proteína HMGA2/genética; Humanos; Proteínas Proto-Oncogénicas c-akt/metabolismo; Factor de Transcripción STAT3/metabolismo; Transducción de Señal/genética; Proteína smad3/metabolismo; Factores de Transcripción de la Familia Snail/metabolismo; Factor A de Crecimiento Endotelial Vascular/metabolismo

Palabras clave

HMGA2; Smad3; Snail-1; apoptosis; colorectal cancer; miR-330

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_colon_rectum_cancers Asunto principal: Neoplasias Colorrectales / Apoptosis / Proteína HMGA2 / MicroARNs / Transición Epitelial-Mesenquimal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Cell Physiol Año: 2020 Tipo del documento: Article País de afiliación: Irán

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google