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7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects.
Kruegel, Andrew C; Uprety, Rajendra; Grinnell, Steven G; Langreck, Cory; Pekarskaya, Elizabeth A; Le Rouzic, Valerie; Ansonoff, Michael; Gassaway, Madalee M; Pintar, John E; Pasternak, Gavril W; Javitch, Jonathan A; Majumdar, Susruta; Sames, Dalibor.
Afiliación
  • Kruegel AC; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Uprety R; Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Grinnell SG; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Langreck C; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Pekarskaya EA; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Le Rouzic V; Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Ansonoff M; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Gassaway MM; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Pintar JE; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Pasternak GW; Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Javitch JA; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Majumdar S; Department of Chemistry, Department of Psychiatry, Department of Pharmacology, Department of Neuroscience, Columbia University, New York, New York 10027, United States.
  • Sames D; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, New York 10032, United States.
ACS Cent Sci ; 5(6): 992-1001, 2019 Jun 26.
Article en En | MEDLINE | ID: mdl-31263758
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Cent Sci Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Cent Sci Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos