Timing Is Everything: Impact of Naturally Occurring <i>Staphylococcus aureus</i> AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction.

Sloan, Tim J; Murray, Ewan; Yokoyama, Maho; Massey, Ruth C; Chan, Weng C; Bonev, Boyan B; Williams, Paul

Timing Is Everything: Impact of Naturally Occurring Staphylococcus aureus AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction.

Sloan, Tim J; Murray, Ewan; Yokoyama, Maho; Massey, Ruth C; Chan, Weng C; Bonev, Boyan B; Williams, Paul.

Afiliación

Sloan TJ; Centre for Biomolecular Sciences, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom tim.sloan@nottingham.ac.uk paul.williams@nottingham.ac.uk.
Murray E; Centre for Biomolecular Sciences, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Yokoyama M; Centre for Biomolecular Sciences, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Massey RC; School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom.
Chan WC; School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, United Kingdom.
Bonev BB; Centre for Biomolecular Sciences, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Williams P; Centre for Biomolecular Sciences, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom tim.sloan@nottingham.ac.uk paul.williams@nottingham.ac.uk.

J Bacteriol ; 201(20)2019 10 15.

Article en En | MEDLINE | ID: mdl-31358609

Asunto(s)

Sustitución de Aminoácidos; Proteínas Bacterianas/química; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Péptidos Cíclicos/metabolismo; Proteínas Quinasas/química; Proteínas Quinasas/genética; Staphylococcus aureus/metabolismo; Adenosina Trifosfato/metabolismo; Sitios de Unión; Citoplasma/metabolismo; Modelos Moleculares; Simulación de Dinámica Molecular; Fosforilación; Unión Proteica; Dominios Proteicos; Proteínas Quinasas/metabolismo; Multimerización de Proteína; Estructura Secundaria de Proteína; Percepción de Quorum; Staphylococcus aureus/genética; Staphylococcus aureus/patogenicidad; Factores de Tiempo; Transactivadores/metabolismo

Palabras clave

AgrC; Staphylococcus aureus; accessory gene regulator (agr); autoinducing peptide (AIP); exotoxins; molecular dynamics; quorum sensing; sensor kinase; virulence

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Proteínas Quinasas / Staphylococcus aureus / Proteínas Bacterianas / Sustitución de Aminoácidos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Bacteriol Año: 2019 Tipo del documento: Article

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