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Involvement of noncoding RNAs in epigenetic modifications of esophageal cancer.
Xiao, Yuhang; Su, Min; Ou, Wei; Wang, Hui; Tian, Bo; Ma, Junliang; Tang, Jinming; Wu, Jie; Wu, Zhining; Wang, Wenxiang; Zhou, Yong.
Afiliación
  • Xiao Y; Department of Pharmacy, Xiangya Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Su M; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China; Hunan Key Laboratory of Translational Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya
  • Ou W; Department of Pharmacy, The First People's Hospital of Yue Yang, Yue Yang, PR China.
  • Wang H; Hunan Key Laboratory of Translational Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Tian B; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Ma J; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Tang J; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Wu J; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Wu Z; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China.
  • Wang W; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China; Hunan Key Laboratory of Translational Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya
  • Zhou Y; Department of the 2nd Thoracic Surgery, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, PR China. Electronic address: zhouyong_hnszlyy@163.com.
Biomed Pharmacother ; 117: 109192, 2019 Sep.
Article en En | MEDLINE | ID: mdl-31387188
ABSTRACT
Esophageal cancer (EC) is a serious digestive malignancy and is a leading cause of cancer-related mortality. Apart from genetic mutations, many epigenetic alterations including DNA methylation and histone modifications associated with chromatin remodeling have been identified in the regulation of gene expression in EC. Recently, noncoding RNAs, and mainly lncRNAs and miRNAs, have been revealed to be involved in the epigenetic regulation of EC. In this review, we focus on describing new insights on epigenetic processes associated with noncoding RNAs, which have been characterized to be responsible for the development and progression of EC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / ARN no Traducido / Epigénesis Genética Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / ARN no Traducido / Epigénesis Genética Límite: Humans Idioma: En Revista: Biomed Pharmacother Año: 2019 Tipo del documento: Article