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Synthesis, biological evaluation and mechanism studies of C-23 modified 23-hydroxybetulinic acid derivatives as anticancer agents.
Lu, Lixue; Zhang, Hengyuan; Liu, Jie; Liu, Yang; Wang, Yiwei; Xu, Shengtao; Zhu, Zheying; Xu, Jinyi.
Afiliación
  • Lu L; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China; Department of Organic Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China.
  • Zhang H; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China.
  • Liu J; Department of Organic Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China. Electronic address: cpu-jill@163.com.
  • Liu Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China.
  • Wang Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China.
  • Xu S; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China.
  • Zhu Z; Division of Molecular Therapeutics & Formulation, School of Pharmacy, The University of Nottingham, University Park Campus, Nottingham, NG7 2RD, UK.
  • Xu J; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, 210009, PR China. Electronic address: jinyixu@china.com.
Eur J Med Chem ; 182: 111659, 2019 Nov 15.
Article en En | MEDLINE | ID: mdl-31491611
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos / Antineoplásicos Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2019 Tipo del documento: Article