Derailing the aspartate pathway of Mycobacterium tuberculosis to eradicate persistent infection.

Hasenoehrl, Erik J; Rae Sajorda, Dannah; Berney-Meyer, Linda; Johnson, Samantha; Tufariello, JoAnn M; Fuhrer, Tobias; Cook, Gregory M; Jacobs, William R; Berney, Michael

Hasenoehrl, Erik J; Rae Sajorda, Dannah; Berney-Meyer, Linda; Johnson, Samantha; Tufariello, JoAnn M; Fuhrer, Tobias; Cook, Gregory M; Jacobs, William R; Berney, Michael.

Afiliación

Hasenoehrl EJ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Rae Sajorda D; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Berney-Meyer L; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Johnson S; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Tufariello JM; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Fuhrer T; Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA.
Cook GM; Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, Zurich, Switzerland.
Jacobs WR; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, 9054, New Zealand.
Berney M; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland, 1042, New Zealand.

Nat Commun ; 10(1): 4215, 2019 09 16.

Article en En | MEDLINE | ID: mdl-31527595

Asunto(s)

Ácido Aspártico/metabolismo; Mycobacterium tuberculosis/metabolismo; Antituberculosos/farmacología; Humanos; Lisina/metabolismo; Mycobacterium tuberculosis/efectos de los fármacos; Mycobacterium tuberculosis/genética; Treonina/metabolismo; Tuberculosis/microbiología

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 / 3_ND / 4_TD Problema de salud: 1_doencas_transmissiveis / 2_enfermedades_transmissibles / 3_neglected_diseases / 3_tuberculosis / 4_tuberculosis Asunto principal: Ácido Aspártico / Mycobacterium tuberculosis Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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