A highly selective "turn-on" electroanalysis strategy with reduced copper metal-organic frameworks for sensing histamine and histidine.
Nanoscale
; 11(37): 17401-17406, 2019 Oct 07.
Article
en En
| MEDLINE
| ID: mdl-31528930
ABSTRACT
A highly selective and sensitive electroanalysis strategy has been developed for sensing histamine (HTA) and histidine (His) with "turn-on" signal outputs using copper nanocomposites (Cu NCs) of reduced copper metal-organic frameworks (Cu MOFs). It was discovered that the Cu NC-modified electrodes could display the sharp and stable oxidation peaks of solid-state CuCl electrochemistry at a low potential (about -0.10 V). More interestingly, once HTA or His was introduced, the peaking currents of the electrodes would increase due to the specific interaction between Cu2+ and imidazole groups of HTA or His. A highly selective electroanalysis method was thereby developed for the detection of both HTA and His in the concentration range of 0.010-100 µM. Besides, the application feasibility of the developed electroanalysis strategy was demonstrated for the evaluation of HTA and His separately in red wine and urine samples. Such an electroanalysis candidate for HTA and His holds great potential for wide applications in the fields of food analysis and clinical disease diagnosis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Histamina
/
Cobre
/
Técnicas Electroquímicas
/
Estructuras Metalorgánicas
/
Histidina
Tipo de estudio:
Health_technology_assessment
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Nanoscale
Año:
2019
Tipo del documento:
Article