IL-10-producing regulatory B cells exhibit functional defects and play a protective role in severe endotoxic shock.

Tao, Lei; Wang, Yiyuan; Xu, Jialan; Su, Jianbing; Yang, Qin; Deng, Wende; Zou, Binhua; Tan, Yanhui; Ding, Zongbao; Li, Xiaojuan

Tao, Lei; Wang, Yiyuan; Xu, Jialan; Su, Jianbing; Yang, Qin; Deng, Wende; Zou, Binhua; Tan, Yanhui; Ding, Zongbao; Li, Xiaojuan.

Afiliación

Tao L; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Wang Y; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Xu J; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Su J; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Yang Q; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Deng W; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Zou B; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Tan Y; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Ding Z; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C
Li X; Laboratory of Anti-inflammatory and Immunomodulatory Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China; Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, C

Pharmacol Res ; 148: 104457, 2019 10.

Article en En | MEDLINE | ID: mdl-31536782

Asunto(s)

Linfocitos B Reguladores/inmunología; Interleucina-10/inmunología; Choque Séptico/inmunología; Animales; Antígenos CD1d/inmunología; Linfocitos T CD4-Positivos/inmunología; Antígenos CD5/inmunología; Femenino; Interferón gamma/inmunología; Lipopolisacáridos/inmunología; Activación de Linfocitos/inmunología; Ratones; Ratones Endogámicos C57BL

Palabras clave

5(6)-CFDA N-succinimidyl ester (CFSE, PubChem, CID: 71314542); CD1d; CD4(+) T cells; Endotoxic shock; Eosin (PubChem CID: 11048); Haematoxylin (PubChem CID: 442514); IL-10; Ionomycin (PubChem CID: 6912226); Lipopolysaccharide (PubChem CID: 11970143); Monensin (PubChem CID: 441145); Phorbol 12-myristate 13-acetate (PMA, PubChem CID: 27924); Regulatory B cells

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Choque Séptico / Interleucina-10 / Linfocitos B Reguladores Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2019 Tipo del documento: Article

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