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Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2.
Osawa, Tsuyoshi; Shimamura, Teppei; Saito, Kyoko; Hasegawa, Yoko; Ishii, Naoko; Nishida, Miyuki; Ando, Ritsuko; Kondo, Ayano; Anwar, Muyassar; Tsuchida, Rika; Hino, Shinjiro; Sakamoto, Akihisa; Igarashi, Kaori; Saitoh, Kaori; Kato, Keiko; Endo, Keiko; Yamano, Shotaro; Kanki, Yasuharu; Matsumura, Yoshihiro; Minami, Takashi; Tanaka, Toshiya; Anai, Motonobu; Wada, Youichiro; Wanibuchi, Hideki; Hayashi, Mitsuhiro; Hamada, Akinobu; Yoshida, Masayuki; Yachida, Shinichi; Nakao, Mitsuyoshi; Sakai, Juro; Aburatani, Hiroyuki; Shibuya, Masabumi; Hanada, Kentaro; Miyano, Satoru; Soga, Tomoyoshi; Kodama, Tatsuhiko.
Afiliación
  • Osawa T; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan. Electronic address: osawa@lsbm.org.
  • Shimamura T; Department of Systems Biology, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. Electronic address: shimamura@med.nagoya-u.ac.jp.
  • Saito K; Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
  • Hasegawa Y; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Ishii N; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Nishida M; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Ando R; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Kondo A; Division of Genome Science, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Anwar M; Division of Genome Science, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Tsuchida R; Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.
  • Hino S; Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan.
  • Sakamoto A; Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan.
  • Igarashi K; Institute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
  • Saitoh K; Institute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
  • Kato K; Institute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
  • Endo K; Institute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan.
  • Yamano S; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
  • Kanki Y; Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan.
  • Matsumura Y; Division of Metabolic Medicine, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Minami T; Division of Molecular and Vascular Biology, IRDA, Kumamoto University, Kumamoto 860-0811, Japan.
  • Tanaka T; Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Anai M; Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Wada Y; Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan.
  • Wanibuchi H; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
  • Hayashi M; Division of Clinical Pharmacology and Translational Research, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Hamada A; Division of Molecular Pharmacology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
  • Yoshida M; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo 104-0045, Japan.
  • Yachida S; Department of Cancer Genome Informatics, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
  • Nakao M; Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan.
  • Sakai J; Division of Metabolic Medicine, RCAST, The University of Tokyo, Tokyo 153-8904, Japan; Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan.
  • Aburatani H; Division of Genome Science, RCAST, The University of Tokyo, Tokyo 153-8904, Japan.
  • Shibuya M; Institute of Physiology and Medicine, Jobu University, 634-1 Toyazuka-machi, Isesaki, Gunma 372-8588, Japan.
  • Hanada K; Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
  • Miyano S; Human Genome Center, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
  • Soga T; Institute for Advanced Biosciences, Keio University, Tsuruoka 997-0052, Japan. Electronic address: soga@sfc.keio.ac.jp.
  • Kodama T; Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, Tokyo 153-8904, Japan. Electronic address: kodama@lsbm.org.
Cell Rep ; 29(1): 89-103.e7, 2019 10 01.
Article en En | MEDLINE | ID: mdl-31577958
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Nucleotidiltransferasas / Inanición / Regulación hacia Abajo / Etanolaminas / Glutamina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Nucleotidiltransferasas / Inanición / Regulación hacia Abajo / Etanolaminas / Glutamina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2019 Tipo del documento: Article