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HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis.
Liang, Chao; Li, Jie; Lu, Cheng; Xie, Duoli; Liu, Jin; Zhong, Chuanxin; Wu, Xiaohao; Dai, Rongchen; Zhang, Huarui; Guan, Daogang; Guo, Baosheng; He, Bing; Li, Fangfei; He, Xiaojuan; Zhang, Wandong; Zhang, Bao-Ting; Zhang, Ge; Lu, Aiping.
Afiliación
  • Liang C; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Li J; Institute of Integrated Bioinfomedicine and Translational Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Lu C; Institute of Precision Medicine and Innovative Drug Discovery, HKBU Institute for Research and Continuing Education, 518000, Shenzhen, China.
  • Xie D; Faculty of Medicine, School of Chinese Medicine, Chinese University of Hong Kong, 999077, Hong Kong SAR, China.
  • Liu J; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Zhong C; Institute of Integrated Bioinfomedicine and Translational Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Wu X; Institute of Precision Medicine and Innovative Drug Discovery, HKBU Institute for Research and Continuing Education, 518000, Shenzhen, China.
  • Dai R; Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, 100700, Beijing, China.
  • Zhang H; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Guan D; Institute of Integrated Bioinfomedicine and Translational Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Guo B; Institute of Precision Medicine and Innovative Drug Discovery, HKBU Institute for Research and Continuing Education, 518000, Shenzhen, China.
  • He B; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Li F; Institute of Integrated Bioinfomedicine and Translational Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • He X; Institute of Precision Medicine and Innovative Drug Discovery, HKBU Institute for Research and Continuing Education, 518000, Shenzhen, China.
  • Zhang W; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Zhang BT; Institute of Integrated Bioinfomedicine and Translational Science, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
  • Zhang G; Institute of Precision Medicine and Innovative Drug Discovery, HKBU Institute for Research and Continuing Education, 518000, Shenzhen, China.
  • Lu A; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, 999077, Hong Kong SAR, China.
Nat Commun ; 10(1): 4579, 2019 10 08.
Article en En | MEDLINE | ID: mdl-31594926
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Resorción Ósea / Subunidad alfa del Factor 1 Inducible por Hipoxia / Leflunamida / Inmunosupresores Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Resorción Ósea / Subunidad alfa del Factor 1 Inducible por Hipoxia / Leflunamida / Inmunosupresores Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: China