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Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue.
Lemme, Marta; Braren, Ingke; Prondzynski, Maksymilian; Aksehirlioglu, Bülent; Ulmer, Bärbel M; Schulze, Mirja L; Ismaili, Djemail; Meyer, Christian; Hansen, Arne; Christ, Torsten; Lemoine, Marc D; Eschenhagen, Thomas.
Afiliación
  • Lemme M; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Braren I; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
  • Prondzynski M; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Aksehirlioglu B; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
  • Ulmer BM; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Schulze ML; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
  • Ismaili D; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, USA.
  • Meyer C; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Hansen A; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Christ T; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
  • Lemoine MD; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
  • Eschenhagen T; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, 20246 Hamburg, Germany.
Cardiovasc Res ; 116(8): 1487-1499, 2020 07 01.
Article en En | MEDLINE | ID: mdl-31598634
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales de Acción / Estimulación Cardíaca Artificial / Taquicardia Ventricular / Miocitos Cardíacos / Células Madre Pluripotentes Inducidas / Optogenética / Channelrhodopsins / Corazón / Frecuencia Cardíaca / Contracción Miocárdica Aspecto: Ethics Límite: Humans Idioma: En Revista: Cardiovasc Res Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Potenciales de Acción / Estimulación Cardíaca Artificial / Taquicardia Ventricular / Miocitos Cardíacos / Células Madre Pluripotentes Inducidas / Optogenética / Channelrhodopsins / Corazón / Frecuencia Cardíaca / Contracción Miocárdica Aspecto: Ethics Límite: Humans Idioma: En Revista: Cardiovasc Res Año: 2020 Tipo del documento: Article País de afiliación: Alemania