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Novel Metabolites from the Endophytic Fungus Chaetomium subaffine L01.
Han, Xiao-Yang; Xie, Yi-Xuan; Wu, Chao-Qun; Ai, Hong-Lian; Lei, Xin-Xiang; Wang, Xiang-Jing.
Afiliación
  • Han XY; Key Laboratory of Agriculture Biological Functional Gene of Heilongjiang Provincial Education Committee, Northeast Agricultural University, Harbin, 150030, P. R. China.
  • Xie YX; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, 430074, P. R. China.
  • Wu CQ; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, 430074, P. R. China.
  • Ai HL; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, 430074, P. R. China.
  • Lei XX; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, 430074, P. R. China.
  • Wang XJ; Key Laboratory of Agriculture Biological Functional Gene of Heilongjiang Provincial Education Committee, Northeast Agricultural University, Harbin, 150030, P. R. China.
Chem Biodivers ; 16(12): e1900471, 2019 Dec.
Article en En | MEDLINE | ID: mdl-31612620
ABSTRACT
One natural p-terphenyl glycoside, gliocladinin C, and two furano-polyene derivatives, chaetominins A and B, were isolated from potato endophytic fungus Chaetomium subaffine. The absolute configurations of these compounds were elucidated by HR-ESI-MS, NMR, the DP4+ probabilities and electronic circular dichroism (ECD) spectra. Furthermore, gliocladinin C and chaetominin A showed cytotoxic activity against two selected human tumor cell lines (Hep-2 and HepG-2).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Terfenilo / Chaetomium / Antineoplásicos Límite: Humans Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Terfenilo / Chaetomium / Antineoplásicos Límite: Humans Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2019 Tipo del documento: Article