A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90.

Yu, Chen-Yang; Han, Ji-Xuan; Zhang, Junfang; Jiang, Penglei; Shen, Chaoqin; Guo, Fangfang; Tang, Jiayin; Yan, Tingting; Tian, Xianglong; Zhu, Xiaoqiang; Ma, Dan; Hu, Ye; Xie, Yuanhong; Du, Wan; Zhong, Ming; Chen, Jinxian; Liu, Qiang; Sun, Danfeng; Chen, Yingxuan; Zou, Weiping; Hong, Jie; Chen, Haoyan; Fang, Jing-Yuan

Yu, Chen-Yang; Han, Ji-Xuan; Zhang, Junfang; Jiang, Penglei; Shen, Chaoqin; Guo, Fangfang; Tang, Jiayin; Yan, Tingting; Tian, Xianglong; Zhu, Xiaoqiang; Ma, Dan; Hu, Ye; Xie, Yuanhong; Du, Wan; Zhong, Ming; Chen, Jinxian; Liu, Qiang; Sun, Danfeng; Chen, Yingxuan; Zou, Weiping; Hong, Jie; Chen, Haoyan; Fang, Jing-Yuan.

Afiliación

Yu CY; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Han JX; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Zhang J; Key Laboratory of Aquacultural Resources and Utilization, Ministry of Education, College of Fishery and Life Science, Shanghai Ocean University, 201306, Shanghai, China.
Jiang P; Key Laboratory of Aquacultural Resources and Utilization, Ministry of Education, College of Fishery and Life Science, Shanghai Ocean University, 201306, Shanghai, China.
Shen C; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Guo F; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Tang J; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Yan T; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Tian X; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Zhu X; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Ma D; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Hu Y; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Xie Y; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Du W; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Zhong M; Departments of Surgery and Pathology, Center of Excellence for Cancer Immunology and Immunotherapy, the University of Michigan Rogel Cancer Center, Graduate programs in Immunology and Cancer Biology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
Chen J; Division of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, 200001, Shanghai, China.
Liu Q; Division of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, 200001, Shanghai, China.
Sun D; Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, 200001, Shanghai, China.
Chen Y; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Zou W; Departments of Surgery and Pathology, Center of Excellence for Cancer Immunology and Immunotherapy, the University of Michigan Rogel Cancer Center, Graduate programs in Immunology and Cancer Biology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
Hong J; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro
Chen H; Departments of Surgery and Pathology, Center of Excellence for Cancer Immunology and Immunotherapy, the University of Michigan Rogel Cancer Center, Graduate programs in Immunology and Cancer Biology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
Fang JY; State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Ro

Oncogene ; 39(6): 1347-1360, 2020 02.

Article en En | MEDLINE | ID: mdl-31641208

Asunto(s)

Biomarcadores de Tumor/metabolismo; Cromosomas Humanos Par 16/genética; Regulación Neoplásica de la Expresión Génica; Predisposición Genética a la Enfermedad; Polimorfismo de Nucleótido Simple; Proteínas Represoras/metabolismo; Proteínas Represoras/fisiología; Alelos; Animales; Antígenos CD/genética; Apoptosis; Biomarcadores de Tumor/genética; Proteínas Morfogenéticas Óseas/genética; Proteínas Morfogenéticas Óseas/metabolismo; Cadherinas/genética; Proliferación Celular; Estudios de Cohortes; Neoplasias Colorrectales/patología; Estudio de Asociación del Genoma Completo; Humanos; Masculino; Ratones; Ratones Endogámicos NOD; Ratones Noqueados; Ratones SCID; Factores de Transcripción NFATC/genética; Factores de Transcripción NFATC/metabolismo; Pronóstico; Regiones Promotoras Genéticas; Sitios de Carácter Cuantitativo; Proteínas Represoras/genética; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Cromosomas Humanos Par 16 / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article

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