Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis.

Godet, Inês; Shin, Yu Jung; Ju, Julia A; Ye, I Chae; Wang, Guannan; Gilkes, Daniele M

Godet, Inês; Shin, Yu Jung; Ju, Julia A; Ye, I Chae; Wang, Guannan; Gilkes, Daniele M.

Afiliación

Godet I; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.
Shin YJ; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, 21218, USA.
Ju JA; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.
Ye IC; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.
Wang G; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD, 21218, USA.
Gilkes DM; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.

Nat Commun ; 10(1): 4862, 2019 10 24.

Article en En | MEDLINE | ID: mdl-31649238

Asunto(s)

Especies Reactivas de Oxígeno/metabolismo; Esferoides Celulares/metabolismo; Transcriptoma; Hipoxia Tumoral/genética; Animales; Línea Celular Tumoral; Femenino; Humanos; Células MCF-7; Ratones; Ratones Transgénicos; Metástasis de la Neoplasia/genética; Imagen Óptica; Fenotipo; Pronóstico; Microambiente Tumoral

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Especies Reactivas de Oxígeno / Esferoides Celulares / Transcriptoma / Hipoxia Tumoral Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos

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