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The pan-PIM inhibitor INCB053914 displays potent synergy in combination with ruxolitinib in models of MPN.
Mazzacurati, Lucia; Collins, Robert J; Pandey, Garima; Lambert-Showers, Que T; Amin, Narmin E; Zhang, Ling; Stubbs, Matthew C; Epling-Burnette, Pearlie K; Koblish, Holly K; Reuther, Gary W.
Afiliación
  • Mazzacurati L; Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Collins RJ; Incyte Corporation, Wilmington, DE; and.
  • Pandey G; Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Lambert-Showers QT; Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Amin NE; Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Zhang L; Department of Pathology and.
  • Stubbs MC; Incyte Corporation, Wilmington, DE; and.
  • Epling-Burnette PK; Department of Immunology, Moffitt Cancer Center and Research Institute, Tampa, FL.
  • Koblish HK; Incyte Corporation, Wilmington, DE; and.
  • Reuther GW; Department of Molecular Oncology, Moffitt Cancer Center and Research Institute, Tampa, FL.
Blood Adv ; 3(22): 3503-3514, 2019 11 26.
Article en En | MEDLINE | ID: mdl-31725895
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Inhibidores de las Cinasas Janus Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Adv Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Inhibidores de las Cinasas Janus Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Blood Adv Año: 2019 Tipo del documento: Article