Oxyresveratrol drives caspase-independent apoptosis-like cell death in MDA-MB-231 breast cancer cells through the induction of ROS.

Sunilkumar, Damu; Drishya, G; Chandrasekharan, Aneesh; Shaji, Sanu K; Bose, Chinchu; Jossart, Jennifer; Perry, J Jefferson P; Mishra, Nandita; Kumar, Geetha B; Nair, Bipin G

Sunilkumar, Damu; Drishya, G; Chandrasekharan, Aneesh; Shaji, Sanu K; Bose, Chinchu; Jossart, Jennifer; Perry, J Jefferson P; Mishra, Nandita; Kumar, Geetha B; Nair, Bipin G.

Afiliación

Sunilkumar D; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India. Electronic address: damubiotec@gmail.com.
Drishya G; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India.
Chandrasekharan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala 695014, India.
Shaji SK; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India.
Bose C; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India.
Jossart J; Department of Biochemistry, University of California, Riverside, Riverside, CA 92521,USA.
Perry JJP; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India; Department of Biochemistry, University of California, Riverside, Riverside, CA 92521,USA.
Mishra N; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India.
Kumar GB; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India.
Nair BG; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O., Kollam, Kerala 690525, India. Electronic address: bipin@am.amrita.edu.

Biochem Pharmacol ; 173: 113724, 2020 03.

Article en En | MEDLINE | ID: mdl-31756327

Asunto(s)

Apoptosis/efectos de los fármacos; Neoplasias de la Mama/metabolismo; Caspasas/metabolismo; Mitocondrias/efectos de los fármacos; Extractos Vegetales/farmacología; Especies Reactivas de Oxígeno/metabolismo; Estilbenos/farmacología; Antineoplásicos/química; Antineoplásicos/metabolismo; Antineoplásicos/farmacología; Neoplasias de la Mama/patología; Caspasa 3/química; Caspasa 3/metabolismo; Caspasas/química; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Femenino; Humanos; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Mitocondrias/metabolismo; Simulación del Acoplamiento Molecular; Extractos Vegetales/química; Extractos Vegetales/metabolismo; Unión Proteica; Estilbenos/química; Estilbenos/metabolismo

Palabras clave

Apoptosis inducing factor; Breast cancer; Caspase-independent cell death; Oxyresveratrol; Reactive oxygen species

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Estilbenos / Neoplasias de la Mama / Extractos Vegetales / Especies Reactivas de Oxígeno / Apoptosis / Caspasas / Mitocondrias Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Biochem Pharmacol Año: 2020 Tipo del documento: Article

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