ASK1 inhibition triggers platelet apoptosis <i>via</i> p38-MAPK-mediated mitochondrial dysfunction.

Manikanta, Kurnegala; Naveen Kumar, Somanathapura K; Hemshekhar, Mahadevappa; Kemparaju, Kempaiah; Girish, Kesturu S

ASK1 inhibition triggers platelet apoptosis via p38-MAPK-mediated mitochondrial dysfunction.

Manikanta, Kurnegala; Naveen Kumar, Somanathapura K; Hemshekhar, Mahadevappa; Kemparaju, Kempaiah; Girish, Kesturu S.

Afiliación

Manikanta K; Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysuru.
Naveen Kumar SK; Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysuru.
Hemshekhar M; Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysuru.
Kemparaju K; Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysuru ksgbaboo@gmail.com kemparajuom@gmail.com.
Girish KS; Department of Studies in Biochemistry, University of Mysore, Manasagangotri, Mysuru ksgbaboo@gmail.com kemparajuom@gmail.com.

Haematologica ; 105(8): e419-e423, 2020 08.

Article en En | MEDLINE | ID: mdl-31780630

Asunto(s)

Apoptosis; Plaquetas; MAP Quinasa Quinasa Quinasa 5; Mitocondrias/patología; Proteínas Quinasas p38 Activadas por Mitógenos; Animales; Ratones; Especies Reactivas de Oxígeno

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaquetas / Apoptosis / MAP Quinasa Quinasa Quinasa 5 / Proteínas Quinasas p38 Activadas por Mitógenos / Mitocondrias Límite: Animals Idioma: En Revista: Haematologica Año: 2020 Tipo del documento: Article

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