Retinal Thickness Analysis in High Myopia based on Medial Axis Transforms.

This paper presents a retinal thickness analysis method from 3D images acquired by optical coherence tomography (OCT). Given OCT images with segmented boundaries of retinal layers, medial axes of the layers are computed by medial axis transforms (MAT), and thickness is evaluated based on Euclidean distance fields. Since the MAT computes the closest points on the boundary of the layer, it can compute more correct thickness than conventional methods that evaluate Y-axis-aligned thickness. Experimental results show that our method can detect thin-parts around distorted regions, or a clue of high myopia. This is useful for early diagnosis of high myopia and other eye diseases.