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Antibiotic Use for Inpatient Bronchiolitis: Did National Guidelines Impact Practice at a Pediatric Hospital?
Lopez, Alison Ashwini; Aslanova, Rana; Bridger, Natalie; Chafe, Roger.
Afiliación
  • Lopez AA; Independent scholar, Calgary, Alberta, Canada; and alison.lopez17@gmail.com.
  • Aslanova R; Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
  • Bridger N; Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
  • Chafe R; Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
Hosp Pediatr ; 10(2): 147-152, 2020 02.
Article en En | MEDLINE | ID: mdl-31953374
ABSTRACT
BACKGROUND AND

OBJECTIVES:

Bronchiolitis is a common lower respiratory tract infection that affects infants and young children. Because of variability in physician practice, inpatient management varies among pediatricians. In 2014, the Canadian Pediatric Society published national guidelines aimed at standardizing the inpatient management of this illness, which included recommending against the need for antibiotics for most patients. The study objective was to evaluate antibiotic prescription and supportive investigations for inpatient management of bronchiolitis before and after the publication of national guidelines.

METHODS:

This study was a single-center retrospective chart review of inpatients with bronchiolitis. We included healthy children 1 to 24 months of age who were admitted from November 2011 to October 2016. Those admitted before December 2014 were analyzed in the preguidelines cohort; the remaining, in the postguidelines cohort. The main outcome was antibiotic prescription. The secondary outcome was the frequency of chest radiographs, nasopharyngeal swabs, and blood cultures.

RESULTS:

A total of 131 patients were included in the first cohort; 71, in the second cohort. The rates of antibiotic initiation were almost equal in both cohorts (∼44%; P = .98). More antibiotics were discontinued during hospitalization in the second cohort compared with the first cohort (10% vs 20%; P = .001). Significantly fewer patients were discharged with antibiotics in the second cohort (31% vs 16%; P = .02).

CONCLUSIONS:

Our study revealed a reduction in antibiotic use after the release of national guidelines, illustrating that antibiotic prescribing practices can change. However, there is still a pressing need for local initiatives to continue to reduce the unnecessary use of antibiotics within the pediatric setting.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Bronquiolitis / Pacientes Internos / Antibacterianos Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Child, preschool / Humans / Infant País/Región como asunto: America do norte Idioma: En Revista: Hosp Pediatr Año: 2020 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Bronquiolitis / Pacientes Internos / Antibacterianos Tipo de estudio: Guideline / Observational_studies / Prognostic_studies Límite: Child, preschool / Humans / Infant País/Región como asunto: America do norte Idioma: En Revista: Hosp Pediatr Año: 2020 Tipo del documento: Article
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