Essential oil of Cymbopogon citratus cultivated in Egypt: seasonal variation in chemical composition and anticholinesterase activity.
Nat Prod Res
; 35(21): 4063-4067, 2021 Nov.
Article
en En
| MEDLINE
| ID: mdl-31960718
ABSTRACT
The yield of essential oil obtained by hydrodistillation of Cymbopogon citratus fresh leaves ranged from 0.15% to 0.46% w/w; being the highest in spring and the lowest in winter. The oil sample obtained in winter exhibited a moderate acetylcholinesterase inhibitory activity (IC50 2.86 ± 0.17 mg/mL), compared to physostigmine (IC50 0.012 mg/mL), while other samples were relatively weak (IC50 values of 2.86-5.40 mg/mL). In all samples, oxygenated monoterpenes were predominating (73.22-89.32%). GC-MS identified a total of 61, 25, 50 and 63 components in oil samples obtained in spring, summer, autumn and winter, respectively. Citral content was the highest in autumn and summer samples (82.02% and 80.01% citral; respectively) and the lowest in winter sample (60.01%). Citral, isolated from the oil demonstrated a relatively potent anticholinesterase activity (IC50 0.21 ± 0.01 mg/mL).
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estaciones del Año
/
Aceites Volátiles
/
Inhibidores de la Colinesterasa
/
Cymbopogon
País/Región como asunto:
Africa
Idioma:
En
Revista:
Nat Prod Res
Año:
2021
Tipo del documento:
Article
País de afiliación:
Egipto