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Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways.
Meng, Xiangqi; Zhao, Yu; Han, Bo; Zha, Caijun; Zhang, Yangong; Li, Ziwei; Wu, Pengfei; Qi, Tengfei; Jiang, Chuanlu; Liu, Yang; Cai, Jinquan.
Afiliación
  • Meng X; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Zhao Y; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials of Ministry of Education, College of Chemistry, Nankai University, 300071, Tianjin, China.
  • Han B; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Zha C; Department of Laboratory Diagnosis, The Second Affiliated Hospital of Harbin Medical University, 150086, Harbin, China.
  • Zhang Y; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Li Z; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Wu P; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Qi T; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China.
  • Jiang C; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China. jcl6688@163.com.
  • Liu Y; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials of Ministry of Education, College of Chemistry, Nankai University, 300071, Tianjin, China. yliu@nankai.edu.cn.
  • Cai J; Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Neuroscience Institute, Heilongjiang Academy of Medical Sciences, 150086, Harbin, China. caijinquan@hrbmu.edu.cn.
Nat Commun ; 11(1): 594, 2020 01 30.
Article en En | MEDLINE | ID: mdl-32001707
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Transducción de Señal / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-met / Nanopartículas / Receptores ErbB / Temozolomida / Glioma Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Transducción de Señal / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-met / Nanopartículas / Receptores ErbB / Temozolomida / Glioma Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: China