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Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments.
Guéret, Stéphanie M; Thavam, Sasikala; Carbajo, Rodrigo J; Potowski, Marco; Larsson, Niklas; Dahl, Göran; Dellsén, Anita; Grossmann, Tom N; Plowright, Alleyn T; Valeur, Eric; Lemurell, Malin; Waldmann, Herbert.
Afiliación
  • Guéret SM; Department of Chemical Biology, AstraZeneca-Max Planck Institute Satellite Unit, Max-Planck-Institute of Molecular Physiology, 44227 Dortmund, Germany.
  • Thavam S; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
  • Carbajo RJ; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, 44227 Dortmund, Germany.
  • Potowski M; Chemistry, Oncology R&D, AstraZeneca, Cambridge CB2 0SL, United Kingdom.
  • Larsson N; Department of Chemical Biology, Max-Planck-Institute of Molecular Physiology, 44227 Dortmund, Germany.
  • Dahl G; Faculty of Chemistry and Chemical Biology, TU Dortmund University, 44227 Dortmund, Germany.
  • Dellsén A; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
  • Grossmann TN; Structure, Biophysics & Fragment Based Lead Generation, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
  • Plowright AT; Mechanistic Biology & Profiling, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
  • Valeur E; Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
  • Lemurell M; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
  • Waldmann H; Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, 431 50 Gothenburg, Sweden.
J Am Chem Soc ; 142(10): 4904-4915, 2020 03 11.
Article en En | MEDLINE | ID: mdl-32058716
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Receptores de Melanocortina / Proteínas Supresoras de la Señalización de Citocinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Receptores de Melanocortina / Proteínas Supresoras de la Señalización de Citocinas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Am Chem Soc Año: 2020 Tipo del documento: Article País de afiliación: Alemania