Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes.

Vakirlis, Nikolaos; Carvunis, Anne-Ruxandra; McLysaght, Aoife

Vakirlis, Nikolaos; Carvunis, Anne-Ruxandra; McLysaght, Aoife.

Afiliación

Vakirlis N; Smurfit Institute of Genetics, Trinity College Dublin, University of Dublin, Dublin, Ireland.
Carvunis AR; Department of Computational and Systems Biology, Pittsburgh Center for Evolutionary Biology and Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, United States.
McLysaght A; Smurfit Institute of Genetics, Trinity College Dublin, University of Dublin, Dublin, Ireland.

Elife ; 92020 02 18.

Article en En | MEDLINE | ID: mdl-32066524

Asunto(s)

Evolución Molecular; Genes/genética; Sintenía/genética; Animales; Secuencia Conservada/genética; Drosophila melanogaster; Humanos; Filogenia; Saccharomyces cerevisiae; Homología de Secuencia

Palabras clave

D. melanogaster; S. cerevisiae; computational biology; conserved synteny; de novo gene emergence; evolution; evolutionary biology; genetic novelty; human; orphan genes; sequence divergence; systems biology

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evolución Molecular / Sintenía / Genes Límite: Animals / Humans Idioma: En Revista: Elife Año: 2020 Tipo del documento: Article País de afiliación: Irlanda

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