Phase I randomized trial of liothyronine for remyelination in multiple sclerosis: A dose-ranging study with assessment of reliability of visual outcomes.

Wooliscroft, Lindsey; Altowaijri, Ghadah; Hildebrand, Andrea; Samuels, Mary; Oken, Barry; Bourdette, Dennis; Cameron, Michelle

Wooliscroft, Lindsey; Altowaijri, Ghadah; Hildebrand, Andrea; Samuels, Mary; Oken, Barry; Bourdette, Dennis; Cameron, Michelle.

Afiliación

Wooliscroft L; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States; Department of Neurology, Department of Veterans Affairs Portland Health Care System, 3710 S.W. U.S. Veterans Hospital Rd., Portland, OR 97239, United States. Elec
Altowaijri G; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States; Department of Neurology, Department of Veterans Affairs Portland Health Care System, 3710 S.W. U.S. Veterans Hospital Rd., Portland, OR 97239, United States.
Hildebrand A; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States; Department of Neurology, Department of Veterans Affairs Portland Health Care System, 3710 S.W. U.S. Veterans Hospital Rd., Portland, OR 97239, United States. Elec
Samuels M; Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, CR107, Portland, OR 97239, United States. Electronic address: samuelsm@ohsu.edu.
Oken B; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States. Electronic address: oken@ohsu.edu.
Bourdette D; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States. Electronic address: bourdett@ohsu.edu.
Cameron M; Department of Neurology, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR L226 97239, United States; Department of Neurology, Department of Veterans Affairs Portland Health Care System, 3710 S.W. U.S. Veterans Hospital Rd., Portland, OR 97239, United States. Elec

Mult Scler Relat Disord ; 41: 102015, 2020 Jun.

Article en En | MEDLINE | ID: mdl-32120028

Asunto(s)

Potenciales Evocados Visuales/efectos de los fármacos; Esclerosis Múltiple/tratamiento farmacológico; Evaluación de Resultado en la Atención de Salud/normas; Remielinización/efectos de los fármacos; Triyodotironina/farmacología; Agudeza Visual/efectos de los fármacos; Adulto; Femenino; Humanos; Masculino; Persona de Mediana Edad; Reproducibilidad de los Resultados; Triyodotironina/administración & dosificación; Triyodotironina/efectos adversos

Palabras clave

Clinical trial; Evoked potentials; Liothyronine; Low contrast letter acuity; Multiple sclerosis; Phase I; Remyelination; Visual

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triyodotironina / Agudeza Visual / Evaluación de Resultado en la Atención de Salud / Potenciales Evocados Visuales / Remielinización / Esclerosis Múltiple Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Mult Scler Relat Disord Año: 2020 Tipo del documento: Article

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