Seroprevalence of Toxoplasma gondii in cattle in China from 2010 to 2019: A systematic review and meta-analysis.

ABSTRACT

Toxoplasma gondii can infect almost all warm-blooded animals, including cattle, causing serious disease to animals and humans. Because cattle provide milk and meat for humans, an increasing number of people are raising cattle as a source of income. However, T. gondii may be transmitted to humans through the meat and milk of cattle. Although substantial relevant studies have been performed, overall data on the seroprevalence of T. gondii in cattle is still lacking. In this meta-analysis, 71 relevant studies were included from five databases that investigated the seroprevalence of T. gondii in cattle in China from 2010 to 2019. The overall pooled T. gondii seroprevalence in cattle was 10.1% (4217/39,274) in China. The seroprevalence of T. gondii was highest in southwestern China (21.6%, 727/3117) and lowest in northern China (4.5%, 185/1966). Due to the implementation of disease control measures during 2012 to 2020, the lowest positive rate was seen in the post-2017 subgroup of sampling years (5.8%, 170/3022). In the cattle breeds subgroups, the seroprevalence was highest in yaks (14.3%, 1695/10,777). Cattle aged ≥12 months (9.6%, 1248/12,438) had a higher seroprevalence than those <12 months (6.7%, 226/3132). Female cattle had a slightly higher seroprevalence (12.5%, 793/6670) than male cattle (11.7%, 418/3856). The seroprevalence in summer (11.8%, 517/4744) was the highest of all seasons. The present study shows that T. gondii is common in cattle in China. Therefore, monitoring measures and further research are needed to control T. gondii and improve public health.