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Temporal activation of WNT/ß-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth.
Uka, Rexhep; Britschgi, Christian; Krättli, Anja; Matter, Claudia; Mihic, Daniela; Okoniewski, Michal J; Gualandi, Marco; Stupp, Roger; Cinelli, Paolo; Dummer, Reinhard; Levesque, Mitchell P; Shakhova, Olga.
Afiliación
  • Uka R; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Britschgi C; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Krättli A; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Matter C; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Mihic D; Department of Surgical Pathology, University Hospital Zurich, University of Zurich, Schmelzbergstrasse 12, 8091, Zurich, UK.
  • Okoniewski MJ; Scientific IT Services ETH Zurich, ETH Zurich, Weinbergstrasse 11, 8092, Zürich, UK.
  • Gualandi M; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Stupp R; Department of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
  • Cinelli P; Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
  • Dummer R; The Lou and Jean Malnati Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
  • Levesque MP; Department of Trauma Surgery, University Hospital Zurich, University of Zurich, Sternwartstrasse 14, 8091, Zürich, UK.
  • Shakhova O; Department of Dermatology, University Hospital Zurich, University of Zurich, Wagistrasse 14, 8952, Schlieren, UK.
Oncogene ; 39(20): 4132-4154, 2020 05.
Article en En | MEDLINE | ID: mdl-32238882
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Regulación Neoplásica de la Expresión Génica / Factores de Transcripción SOXE / Vía de Señalización Wnt / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Melanoma Experimental / Regulación Neoplásica de la Expresión Génica / Factores de Transcripción SOXE / Vía de Señalización Wnt / Proteínas de Neoplasias Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido